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Academic Position: Associate Professor
Department - Division: Medicine - Endocrinology
Research Area: Metabolic syndrome - Nrf2 signalling
Description

Dr. Habeos is currently assistant professor in Endocrinology at the University of Patras Department of Medicine. Rep[resentative publications of his work are:

1. Nrf2 represses FGF21 during long-term high-fat diet-induced obesity in mice. Chartoumpekis D, Ziros PG, Psyrogiannis A, Papavassiliou AG, Kyriazopoulou V, Sykiotis G, Habeos IG. Diabetes. 2011 Aug 18; Epub ahead of print PMID: 21852674

2: Chartoumpekis DV, Ziros PG, Sykiotis GP, Zaravinos A, Psyrogiannis AI, Kyriazopoulou VE, Spandidos DA, Habeos IG. Nrf2 activation diminishes during adipocyte differentiation of ST2 cells. Int J Mol Med. 2011 Jul 29. 3: Chartoumpekis DV, Habeos IG, Ziros PG, Psyrogiannis AI, Kyriazopoulou VE, Papavassiliou AG. Brown Adipose Tissue Responds to Cold and Adrenergic Stimulation by Induction of FGF21. Mol Med. 2011;17 (7-8):736-40.

4: Sykiotis GP, Habeos IG, Samuelson AV, Bohmann D. The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation. Curr Opin Clin Nutr Metab Care. 2011 Jan;14(1):41-8. Review.

5: Chartoumpekis D, Ziros PG, Psyrogiannis A, Kyriazopoulou V, Papavassiliou AG, Habeos IG. Simvastatin lowers reactive oxygen species level by Nrf2 activation via PI3K/Akt pathway. Biochem Biophys Res Commun. 2010 May 28;396 (2):463-6.

6: Habeos IG, Ziros PG, Chartoumpekis D, Psyrogiannis A, Kyriazopoulou V, Papavassiliou AG. Simvastatin activates Keap1/Nrf2 signaling in rat liver. J Mol Med (Berl). 2008 Nov;86 (11):1279-85

7: Habeos I, Ziros PG, Psyrogiannis A, Vagenakis AG, Papavassiliou AG. Statins and transcriptional regulation: the FXR connection. Biochem Biophys Res Commun. 2005 Aug 26;334 (2):601-5.

8: Ziros PG, Georgakopoulos T, Habeos I, Basdra EK, Papavassiliou AG. Growth hormone attenuates the transcriptional activity of Runx2 by facilitating its physical association with Stat3beta. J Bone Miner Res. 2004 Nov;19(11):1892-904.

9: Ziros PG, Gil AP, Georgakopoulos T, Habeos I, Kletsas D, Basdra EK, Papavassiliou AG. The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells. J Biol Chem. 2002 Jun 28;277(26):23934-41

10: Hadzic E, Habeos I, Raaka BM, Samuels HH. A novel multifunctional motif in the amino-terminal A/B domain of T3Ralpha modulates DNA binding and receptor dimerization. J Biol Chem. 1998 Apr 24;273(17):10270-8.

 
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